EAA2 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2619545

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商品描述
  • 靶点-Target

    EAAT2

  • 反应性

    Human,Rat,Mouse

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    63kD

  • 推荐稀释比

    WB 1:1000-2000;ELISA 1:5000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human EAA2

  • 特异性

    This antibody detects endogenous levels of Human,Rat,Mouse EAA2

  • 基因名称

    SLC1A2 EAAT2 GLT1

  • 蛋白名称

    EAA2

  • 别名

    Excitatory amino acid transporter 2;Glutamate/aspartate transporter II;Sodium-dependent glutamate/aspartate transporter 2;Solute carrier family 1 member 2;

  • Organism-1

    Human

  • 基因ID-1

    6506

  • SwissProt-1

    P43004

  • Organism-2

    Mouse

  • 基因ID-2

    20511

  • SwissProt-2

    P43006

  • Organism-3

    Rat

  • 基因ID-3

    29482

  • SwissProt-3

    P31596

  • 背景

    This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010],

  • 细胞定位

    Cell membrane ; Multi-pass membrane protein .