FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
Erbin
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
155kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Erbin
特异性
This antibody detects endogenous levels of Human Erbin Polyclonal Antibody
基因名称
ERBB2IP ERBIN KIAA1225 LAP2
蛋白名称
Erbin Polyclonal Antibody
别名
Protein LAP2;Densin-180-like protein;Erbb2-interacting protein;Erbin;
Organism-1
Human
基因ID-1
55914
SwissProt-1
Q96RT1
Organism-2
Mouse
基因ID-2
59079
SwissProt-2
Q80TH2
Organism-3
Rat
基因ID-3
25359
SwissProt-3
Q62733
背景
This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Cell junction, hemidesmosome . Nucleus membrane . Basolateral cell membrane . Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity). .
