- 产品信息
商品描述
靶点-Target
CD43
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
44kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CD43 AA range: 1-80
特异性
This antibody detects endogenous levels of Human CD43
基因名称
SPN CD43
蛋白名称
CD43
别名
Leukosialin;Galactoglycoprotein;GALGP;Leukocyte sialoglycoprotein;Sialophorin;CD antigen CD43;
Organism-1
Human
基因ID-1
6693
SwissProt-1
P16150
Organism-2
Mouse
基因ID-2
20737
SwissProt-2
P15702
Organism-3
Rat
SwissProt-3
P13838
背景
The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response. [provided by RefSeq, Sep 2011],
细胞定位
Membrane ; Single-pass type I membrane protein . Cell projection, microvillus . Cell projection, uropodium . Localizes to the uropodium and microvilli via its interaction with ERM proteins (EZR, RDX and MSN). .; [CD43 cytoplasmic tail]: Nucleus . Nucleus, PML body . The sumoylated form localizes to the PML body. .





