- 产品信息
商品描述
靶点-Target
PD1
反应性
Human,Mouse
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
32kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Pdcd-1 AA range: 80-130
特异性
This antibody detects endogenous levels of Human Pdcd-1
基因名称
PDCD1 PD1
蛋白名称
Pdcd-1
别名
Programmed cell death protein 1;Protein PD-1;hPD-1;CD antigen CD279;
Organism-1
Human
基因ID-1
5133
SwissProt-1
Q15116
Organism-2
Mouse
基因ID-2
18566
SwissProt-2
Q02242
背景
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane ; Single-pass type I membrane protein.





