14-3-3-pan rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2619443

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商品描述
  • 靶点-Target

    14-3-3-pan

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,ELISA

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    27kD

  • MW(Observed)

    30kD

  • 推荐稀释比

    WB 1:1000-2000;ELISA 1:5000-20000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human 14-3-3-pan

  • 特异性

    This antibody detects endogenous levels of Human,Mouse,Rat 14-3-3-pan

  • 基因名称

    YWHAB

  • 蛋白名称

    14-3-3-pan

  • 别名

    14-3-3 protein beta/alpha;Protein 1054;Protein kinase C inhibitor protein 1;KCIP-1;[Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]

  • Organism-1

    Human

  • 基因ID-1

    7529

  • SwissProt-1

    P31946;P61981;P27348;P63104;P31947

  • Organism-2

    Mouse

  • 基因ID-2

    54401

  • SwissProt-2

    Q9CQV8

  • Organism-3

    Rat

  • 基因ID-3

    56011

  • SwissProt-3

    P35213

  • 背景

    This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.; Vacuole membrane . (Microbial infection) Upon infection with Chlamydia trachomatis, this protein is associated with the pathogen-containing vacuole membrane where it colocalizes with IncG. .