- 产品信息
商品描述
靶点-Target
Kir4.1
反应性
Human,Rat,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
42kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human Kir4.1 AA range: 160-240
特异性
This antibody detects endogenous levels of Human,Rat,Mouse Kir4.1
基因名称
KCNJ10
蛋白名称
Kir4.1
别名
ATP-sensitive inward rectifier potassium channel 10;ATP-dependent inwardly rectifying potassium channel Kir4.1;Inward rectifier K;+;channel Kir1.2;Potassium channel, inwardly rectifying subfamily J member 10;
Organism-1
Human
基因ID-1
3766
SwissProt-1
P78508
Organism-2
Mouse
基因ID-2
16513
SwissProt-2
Q9JM63
Organism-3
Rat
基因ID-3
29718
SwissProt-3
P49655
背景
This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes. [provided by RefSeq, Jul 2008],
细胞定位
Membrane ; Multi-pass membrane protein. Basolateral cell membrane . In kidney distal convoluted tubules, located in the basolateral membrane where it colocalizes with KCNJ16. .





