- 产品信息
商品描述
靶点-Target
AMPKβ2
反应性
Human,Rat,Mouse,
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
30kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human AMPKβ2 AA range: 130-210
特异性
This antibody detects endogenous levels of Human AMPKβ2
基因名称
PRKAB2
蛋白名称
AMPKβ2
别名
5'-AMP-activated protein kinase subunit beta-2;AMPK subunit beta-2;
Organism-1
Human
基因ID-1
5565
SwissProt-1
O43741
Organism-2
Mouse
基因ID-2
108097
SwissProt-2
Q6PAM0
Organism-3
Rat
基因ID-3
64562
SwissProt-3
Q9QZH4
背景
function:AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit, may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.,PTM:Phosphorylated when associated with the catalytic subunit.,similarity:Belongs to the 5'-AMP-activated protein kinase beta subunit family.,subunit:Heterotrimer of an alpha catalytic subunit, a beta and a gamma non-catalytic regulatory subunits.,





