- 产品信息
商品描述
靶点-Target
EphA4
反应性
Human,Mouse
应用
WB,ELISA
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
108kD
推荐稀释比
WB 1:1000-2000;ELISA 1:5000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human EphA4 AA range: 540-620
特异性
This antibody detects endogenous levels of Human EphA4
基因名称
EPHA4 HEK8 SEK TYRO1
蛋白名称
EphA4
别名
Ephrin type-A receptor 4;EPH-like kinase 8;EK8;hEK8;Tyrosine-protein kinase TYRO1;Tyrosine-protein kinase receptor SEK;
Organism-1
Human
基因ID-1
2043
SwissProt-1
P54764
Organism-2
Mouse
基因ID-2
13838
SwissProt-2
Q03137
背景
This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2015],
细胞定位
Cell membrane ; Single-pass type I membrane protein . Cell projection, axon . Cell projection, dendrite . Cell junction, synapse, postsynaptic density membrane . Early endosome . Cell junction, adherens junction . Clustered upon activation and targeted to early endosome. .





