FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PRGC2
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
113kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PRGC2 AA range: 829-879
特异性
This antibody detects endogenous levels of PRGC2 at Human/Mouse/Rat
基因名称
PPARGC1B PERC PGC1 PGC1B PPARGC1
蛋白名称
PRGC2
Organism-1
Human
基因ID-1
133522
SwissProt-1
Q86YN6
Organism-2
Mouse
基因ID-2
170826
SwissProt-2
Q8VHJ7
Organism-3
Rat
基因ID-3
291567
SwissProt-3
Q811R2
背景
The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010],
细胞定位
Nucleus .
