FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FAN1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
112kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FAN1 AA range: 801-851
特异性
This antibody detects endogenous levels of FAN1 at Human/Mouse
基因名称
FAN1 KIAA1018 MTMR15
蛋白名称
FAN1
Organism-1
Human
基因ID-1
22909
SwissProt-1
Q9Y2M0
Organism-2
Mouse
基因ID-2
330554
SwissProt-2
Q69ZT1
背景
This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016],
细胞定位
Nucleus . Localizes at sites of DNA damage following recruitment by monoubiquitinated FANCD2 (PubMed:20603015, PubMed:20603016). Localizes to stalled replication forks via its UBZ4-type zinc finger (PubMed:20935496). .
