FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RN139
反应性
Human,Mouse
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
73kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human RN139 AA range: 10-60
特异性
This antibody detects endogenous levels of RN139 at Human/Mouse
基因名称
RNF139 TRC8
蛋白名称
RN139
Organism-1
Human
基因ID-1
11236
SwissProt-1
Q8WU17
Organism-2
Mouse
基因ID-2
75841
SwissProt-2
Q7TMV1
背景
The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
