- 产品信息
商品描述
靶点-Target
DAD1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
12kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DAD1 AA range: 38-88
特异性
This antibody detects endogenous levels of DAD1 at Human/Mouse/Rat
基因名称
DAD1
蛋白名称
DAD1
Organism-1
Human
基因ID-1
1603
SwissProt-1
P61803
Organism-2
Mouse
基因ID-2
13135
SwissProt-2
P61804
Organism-3
Rat
基因ID-3
192275
SwissProt-3
P61805
背景
DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum membrane; Multi-pass membrane protein .





