DAD1 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2619220

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商品描述
  • 靶点-Target

    DAD1

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    12kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human DAD1 AA range: 38-88

  • 特异性

    This antibody detects endogenous levels of DAD1 at Human/Mouse/Rat

  • 基因名称

    DAD1

  • 蛋白名称

    DAD1

  • Organism-1

    Human

  • 基因ID-1

    1603

  • SwissProt-1

    P61803

  • Organism-2

    Mouse

  • 基因ID-2

    13135

  • SwissProt-2

    P61804

  • Organism-3

    Rat

  • 基因ID-3

    192275

  • SwissProt-3

    P61805

  • 背景

    DAD1, the defender against apoptotic cell death, was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature, suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme, thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Endoplasmic reticulum membrane; Multi-pass membrane protein .