- 产品信息
商品描述
靶点-Target
SYNJ2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
165kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SYNJ2 AA range: 145-195
特异性
This antibody detects endogenous levels of SYNJ2 at Human/Mouse/Rat
基因名称
SYNJ2 KIAA0348
蛋白名称
SYNJ2
Organism-1
Human
基因ID-1
8871
SwissProt-1
O15056
Organism-2
Mouse
基因ID-2
20975
SwissProt-2
Q9D2G5
Organism-3
Rat
基因ID-3
84018
SwissProt-3
O55207
背景
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010],
细胞定位
Cytoplasm . Cell membrane . Membrane raft . Cell junction, synapse, presynapse . Cytoplasm, cytoskeleton . Localizes at presynapse terminals in brain and at bundles of microtubules surrounding the nucleus in the elongating spermatids corresponding to the manchette (By similarity). Translocates from the cytoplasm to membrane ruffles in a RAC1-dependent manner (PubMed:11084340). .





