FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
UBP18
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
41kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human UBP18 AA range: 66-116
特异性
This antibody detects endogenous levels of UBP18 at Human/Mouse
基因名称
USP18 ISG43
蛋白名称
UBP18
Organism-1
Human
基因ID-1
11274
SwissProt-1
Q9UMW8
Organism-2
Mouse
基因ID-2
24110
SwissProt-2
Q9WTV6
背景
The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011],
细胞定位
[Isoform 1]: Cytoplasm .; [Isoform 2]: Nucleus . Cytoplasm .
