FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
RN103
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
75kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human RN103 AA range: 243-293
特异性
This antibody detects endogenous levels of RN103 at Human/Mouse/Rat
基因名称
RNF103 ZFP103
蛋白名称
RN103
Organism-1
Human
基因ID-1
7844
SwissProt-1
O00237
Organism-2
Mouse
基因ID-2
22644
SwissProt-2
Q9R1W3
Organism-3
Rat
SwissProt-3
Q9EPZ8
背景
The protein encoded by this gene contains a RING-H2 finger, a motif known to be involved in protein-protein and protein-DNA interactions. This gene is highly expressed in normal cerebellum, but not in the cerebral cortex. The expression of the rat counterpart in the frontal cortex and hippocampus was shown to be induced by elctroconvulsive treatment (ECT) as well as chronic antidepressant treatment, suggesting that this gene may be a molecular target for ECT and antidepressants. The protein is a ubiquitin ligase that functions in the endoplasmic reticulum-associated degradation pathway. Alternative splicing of this gene results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream CHMP3 (charged multivesicular body protein 3) gene. [provided by RefSeq, Oct 2011],
细胞定位
Endoplasmic reticulum membrane ; Multi-pass membrane protein .
