TMPS2 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2619127

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商品描述
  • 靶点-Target

    TMPS2

  • 反应性

    Human,Mouse

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    54kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human TMPS2 AA range: 98-148

  • 特异性

    This antibody detects endogenous levels of TMPS2 at Human/Mouse

  • 基因名称

    TMPRSS2 PRSS10

  • 蛋白名称

    TMPS2

  • Organism-1

    Human

  • 基因ID-1

    7113

  • SwissProt-1

    O15393

  • Organism-2

    Mouse

  • 基因ID-2

    50528

  • SwissProt-2

    Q9JIQ8

  • 背景

    This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],

  • 细胞定位

    Cell membrane ; Single-pass type II membrane protein .; [Transmembrane protease serine 2 catalytic chain]: Secreted . Activated by cleavage and secreted. .