- 产品信息
商品描述
靶点-Target
TMPS2
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
54kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TMPS2 AA range: 98-148
特异性
This antibody detects endogenous levels of TMPS2 at Human/Mouse
基因名称
TMPRSS2 PRSS10
蛋白名称
TMPS2
Organism-1
Human
基因ID-1
7113
SwissProt-1
O15393
Organism-2
Mouse
基因ID-2
50528
SwissProt-2
Q9JIQ8
背景
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
细胞定位
Cell membrane ; Single-pass type II membrane protein .; [Transmembrane protease serine 2 catalytic chain]: Secreted . Activated by cleavage and secreted. .





