- 产品信息
商品描述
靶点-Target
P4HA1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
59kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human P4HA1 AA range: 461-511
特异性
This antibody detects endogenous levels of P4HA1 at Human/Mouse/Rat
基因名称
P4HA1 P4HA
蛋白名称
P4HA1
Organism-1
Human
基因ID-1
5033
SwissProt-1
P13674
Organism-2
Mouse
基因ID-2
18451
SwissProt-2
Q60715
Organism-3
Rat
基因ID-3
64475
SwissProt-3
P54001
背景
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008],
细胞定位
Endoplasmic reticulum lumen.





