FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NOSTN
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
56kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NOSTN AA range: 309-359
特异性
This antibody detects endogenous levels of NOSTN at Human/Mouse/Rat
基因名称
NOSTRIN
蛋白名称
NOSTN
Organism-1
Human
基因ID-1
115677
SwissProt-1
Q8IVI9
Organism-2
Mouse
基因ID-2
329416
SwissProt-2
Q6WKZ7
Organism-3
Rat
基因ID-3
311111
SwissProt-3
Q5I0D6
背景
Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM, Apr 2004],
细胞定位
[Isoform 1]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasmic vesicle . Cytoplasm, cytoskeleton . Enriched in selected actin structures (PubMed:16234328, PubMed:16376344).; [Isoform 3]: Nucleus .
