- 产品信息
商品描述
靶点-Target
GRIK3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
101kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GRIK3 AA range: 209-259
特异性
This antibody detects endogenous levels of GRIK3 at Human/Mouse/Rat
基因名称
GRIK3 GLUR7
蛋白名称
GRIK3
Organism-1
Human
基因ID-1
2899
SwissProt-1
Q13003
Organism-2
Mouse
基因ID-2
14807
SwissProt-2
B1AS29
Organism-3
Rat
基因ID-3
298521
SwissProt-3
P42264
背景
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008],
细胞定位
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.





