FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PTF1A
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
36kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PTF1A AA range: 172-222
特异性
This antibody detects endogenous levels of PTF1A at Human/Mouse/Rat
基因名称
PTF1A BHLHA29 PTF1P48
蛋白名称
PTF1A
Organism-1
Human
基因ID-1
256297
SwissProt-1
Q7RTS3
Organism-2
Mouse
基因ID-2
19213
SwissProt-2
Q9QX98
Organism-3
Rat
基因ID-3
117034
SwissProt-3
Q64305
背景
This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . In chronic pancreatitis associated with pancreas cancer preferentially accumulates in the cytoplasm of acinar/ductular complexes. In the cytoplasm loses its ability to form the PTF1 complex (By similarity). .
