FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
EXOC4
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
107kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human EXOC4 AA range: 512-562
特异性
This antibody detects endogenous levels of EXOC4 at Human/Mouse/Rat
基因名称
EXOC4 KIAA1699 SEC8 SEC8L1
蛋白名称
EXOC4
Organism-1
Human
基因ID-1
60412
SwissProt-1
Q96A65
Organism-2
Mouse
基因ID-2
20336
SwissProt-2
O35382
Organism-3
Rat
基因ID-3
116654
SwissProt-3
Q62824
背景
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],
细胞定位
Midbody, Midbody ring . Cell projection . Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). Localizes at the leading edge of migrating cells (By similarity). .
