- 产品信息
商品描述
靶点-Target
CPSF5
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
25kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human CPSF5 AA range: 25-75
特异性
This antibody detects endogenous levels of CPSF5 at Human/Mouse/Rat
基因名称
NUDT21 CFIM25 CPSF25 CPSF5
蛋白名称
CPSF5
Organism-1
Human
基因ID-1
11051
SwissProt-1
O43809
Organism-2
Mouse
基因ID-2
68219
SwissProt-2
Q9CQF3
Organism-3
Rat
基因ID-3
291877
SwissProt-3
Q4KM65
背景
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Cytoplasm . Shuttles between the nucleus and the cytoplasm in a transcription- and XPO1/CRM1-independent manner, most probably in complex with the cleavage factor Im complex (CFIm) (PubMed:19864460). In punctate subnuclear structures localized adjacent to nuclear speckles, called paraspeckles (PubMed:15169763). .





