- 产品信息
商品描述
靶点-Target
ATG12
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
15kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ATG12 AA range: 80-130
特异性
This antibody detects endogenous levels of ATG12 at Human/Mouse/Rat
基因名称
ATG12 APG12 APG12L
蛋白名称
ATG12
Organism-1
Human
基因ID-1
9140
SwissProt-1
O94817
Organism-2
Mouse
基因ID-2
67526
SwissProt-2
Q9CQY1
Organism-3
Rat
基因ID-3
361321
SwissProt-3
Q2TBJ5
背景
Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]).[supplied by OMIM, Mar 2008],
细胞定位
Cytoplasm . Preautophagosomal structure membrane ; Peripheral membrane protein . TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane.





