FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
SPTN2
反应性
Human,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
263kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SPTN2 AA range: 644-694
特异性
This antibody detects endogenous levels of SPTN2 at Human/Rat
基因名称
SPTBN2 KIAA0302 SCA5
蛋白名称
SPTN2
Organism-1
Human
基因ID-1
6712
SwissProt-1
O15020
Organism-3
Rat
基因ID-3
29211
SwissProt-3
Q9QWN8
背景
Spectrins are principle components of a cell's membrane-cytoskeleton and are composed of two alpha and two beta spectrin subunits. The protein encoded by this gene (SPTBN2), is called spectrin beta non-erythrocytic 2 or beta-III spectrin. It is related to, but distinct from, the beta-II spectrin gene which is also known as spectrin beta non-erythrocytic 1 (SPTBN1). SPTBN2 regulates the glutamate signaling pathway by stabilizing the glutamate transporter EAAT4 at the surface of the plasma membrane. Mutations in this gene cause a form of spinocerebellar ataxia, SCA5, that is characterized by neurodegeneration, progressive locomotor incoordination, dysarthria, and uncoordinated eye movements. [provided by RefSeq, Dec 2009],
细胞定位
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex.
