- 产品信息
商品描述
靶点-Target
SESN3
反应性
Human,Mouse
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
54kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SESN3 AA range: 35-85
特异性
This antibody detects endogenous levels of SESN3 at Human/Mouse
基因名称
SESN3 SEST3
蛋白名称
SESN3
Organism-1
Human
基因ID-1
143686
SwissProt-1
P58005
Organism-2
Mouse
基因ID-2
75747
SwissProt-2
Q9CYP7
背景
This gene encodes a member of the sestrin family of stress-induced proteins. The encoded protein reduces the levels of intracellular reactive oxygen species induced by activated Ras downstream of RAC-alpha serine/threonine-protein kinase (Akt) and FoxO transcription factor. The protein is required for normal regulation of blood glucose, insulin resistance and plays a role in lipid storage in obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012],
细胞定位
Cytoplasm .





