FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
NMRL1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
33kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NMRL1 AA range: 179-229
特异性
This antibody detects endogenous levels of NMRL1 at Human/Mouse/Rat
基因名称
NMRAL1 HSCARG
蛋白名称
NMRL1
Organism-1
Human
基因ID-1
57407
SwissProt-1
Q9HBL8
Organism-2
Mouse
基因ID-2
67824
SwissProt-2
Q8K2T1
Organism-3
Rat
SwissProt-3
P86172
背景
This gene encodes an NADPH sensor protein that preferentially binds to NADPH. The encoded protein also negatively regulates the activity of NF-kappaB in a ubiquitylation-dependent manner. It plays a key role in cellular antiviral response by negatively regulating the interferon response factor 3-mediated expression of interferon beta. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015],
细胞定位
Cytoplasm. Cytoplasm, perinuclear region. Nucleus. Under normal redox growth conditions localizes in the cytoplasm and perinuclear region. Nuclear localization is promoted by increased intracellular nitric oxide and reduced NADPH/NADP(+) ratios.
