- 产品信息
商品描述
靶点-Target
NLRC4
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
113kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NLRC4 AA range: 481-531
特异性
This antibody detects endogenous levels of NLRC4 at Human/Mouse/Rat
基因名称
NLRC4 CARD12 CLAN CLAN1 IPAF UNQ6189/PRO20215
蛋白名称
NLRC4
Organism-1
Human
基因ID-1
58484
SwissProt-1
Q9NPP4
Organism-2
Mouse
基因ID-2
268973
SwissProt-2
Q3UP24
Organism-3
Rat
SwissProt-3
F1M649
背景
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014],
细胞定位
Cytoplasm . Cytoplasm, cytosol . Inflammasome .





