- 产品信息
商品描述
靶点-Target
NEUG
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
9kD
推荐稀释比
IHC 1:50-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NEUG AA range: 23-73
特异性
This antibody detects endogenous levels of NEUG at Human/Mouse/Rat
基因名称
NRGN
蛋白名称
NEUG
Organism-1
Human
基因ID-1
4900
SwissProt-1
Q92686
Organism-2
Mouse
基因ID-2
64011
SwissProt-2
P60761
Organism-3
Rat
基因ID-3
64356
SwissProt-3
Q04940
背景
Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008],
细胞定位
nucleus,trans-rk transport vesicle membrane,postsynaptic density,axon,mitochondrial membrane,neuronal cell body,dendritic spine head,





