- 产品信息
商品描述
靶点-Target
TYDP2
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
40kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TYDP2 AA range: 261-311
特异性
This antibody detects endogenous levels of TYDP2 at Human/Mouse/Rat
基因名称
TDP2 EAP2 TTRAP AD-022
蛋白名称
TYDP2
Organism-1
Human
基因ID-1
51567
SwissProt-1
O95551
Organism-2
Mouse
基因ID-2
56196
SwissProt-2
Q9JJX7
Organism-3
Rat
基因ID-3
498749
SwissProt-3
Q3T1H5
背景
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus . Nucleus, PML body . Nucleus, nucleolus . Cytoplasm. Localizes to nucleolar cavities following stress; localization to nucleolus is dependent on PML protein. .; Cytoplasm . (Microbial infection) In case of infection by picornavirus, relocalizes to cytoplasmic sites distinct from those containing viral proteins associated with RNA replication or encapsidation. .





