FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
AQP7
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
38kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human AQP7 AA range: 136-186
特异性
This antibody detects endogenous levels of AQP7 at Human/Mouse/Rat
基因名称
AQP7 AQP7L AQP9
蛋白名称
AQP7
Organism-1
Human
基因ID-1
364
SwissProt-1
O14520
Organism-2
Mouse
基因ID-2
11832
SwissProt-2
O54794
Organism-3
Rat
基因ID-3
29171
SwissProt-3
P56403
背景
This gene encodes a member of the aquaporin family of water-selective membrane channels. The encoded protein localizes to the plasma membrane and allows movement of water, glycerol and urea across cell membranes. This gene is highly expressed in the adipose tissue where the encoded protein facilitates efflux of glycerol. In the proximal straight tubules of kidney, the encoded protein is localized to the apical membrane and prevents excretion of glycerol into urine. The encoded protein is present in spermatids, as well as in the testicular and epididymal spermatozoa suggesting an important role in late spermatogenesis. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. This gene is located adjacent to a related aquaporin gene on chromosome 9. Multiple pseudogenes of this gene have been identified. [provided by RefSeq, Dec 2015],
细胞定位
Cell membrane ; Multi-pass membrane protein . Cytoplasm, cell cortex . Cytoplasmic vesicle membrane ; Multi-pass membrane protein . Lipid droplet . Internalized from the cell membrane in response to catecholamine-induced activation of PKA; detected on intracellular membranes and colocalizes with lipid droplets (By similarity). Colocalizes with PLIN1 in adipocytes, probably on lipid droplets (PubMed:27832861). .
