- 产品信息
商品描述
靶点-Target
AP4A
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
16kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human AP4A AA range: 93-143
特异性
This antibody detects endogenous levels of AP4A at Human/Mouse/Rat
基因名称
NUDT2 APAH1
蛋白名称
AP4A
Organism-1
Human
基因ID-1
318
SwissProt-1
P50583
Organism-2
Mouse
基因ID-2
66401
SwissProt-2
P56380
Organism-3
Rat
基因ID-3
297998
SwissProt-3
Q6PEC0
背景
This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified. [provided by RefSeq, Sep 2011],
细胞定位
mitochondrial matrix,





