- 产品信息
商品描述
靶点-Target
GDF11
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
45kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human GDF11 AA range: 217-267
特异性
This antibody detects endogenous levels of GDF11 at Human/Mouse/Rat
基因名称
GDF11 BMP11
蛋白名称
GDF11
Organism-1
Human
基因ID-1
10220
SwissProt-1
O95390
Organism-2
Mouse
基因ID-2
14561
SwissProt-2
Q9Z1W4
Organism-3
Rat
SwissProt-3
Q9Z217
背景
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein plays a role in the development of the nervous and other organ systems, and may regulate aging. [provided by RefSeq, Aug 2016],
细胞定位
Secreted .





