FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
PDE11
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
103kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human PDE11 AA range: 421-471
特异性
This antibody detects endogenous levels of PDE11 at Human/Mouse/Rat
基因名称
PDE11A
蛋白名称
PDE11
Organism-1
Human
基因ID-1
50940
SwissProt-1
Q9HCR9
Organism-2
Mouse
基因ID-2
241489
SwissProt-2
P0C1Q2
Organism-3
Rat
基因ID-3
140928
SwissProt-3
Q8VID6
背景
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
细胞定位
Cytoplasm, cytosol .
