- 产品信息
商品描述
靶点-Target
ASCC3
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
242kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ASCC3 AA range: 2053-2103
特异性
This antibody detects endogenous levels of ASCC3 at Human/Mouse/Rat
基因名称
ASCC3 HELIC1
蛋白名称
ASCC3
Organism-1
Human
基因ID-1
10973
SwissProt-1
Q8N3C0
Organism-2
Mouse
基因ID-2
77987
SwissProt-2
E9PZJ8
Organism-3
Rat
SwissProt-3
F1LPQ2
背景
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],
细胞定位
Nucleus . Nucleus speckle . Cytoplasm, cytosol . Colocalizes with ALKBH3 and ASCC2 in nuclear foci when cells have been exposed to alkylating agents that cause DNA damage. .





