FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
DUOX1
反应性
Human,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
171kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DUOX1 AA range: 1398-1448
特异性
This antibody detects endogenous levels of DUOX1 at Human/Rat
基因名称
DUOX1 DUOX LNOX1 THOX1
蛋白名称
DUOX1
Organism-1
Human
基因ID-1
53905
SwissProt-1
Q9NRD9
Organism-3
Rat
基因ID-3
266807
SwissProt-3
Q8CIY2
背景
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012],
细胞定位
Apical cell membrane ; Multi-pass membrane protein . Localizes to the apical membrane of epithelial cells.
