FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
FACR1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
57kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human FACR1 AA range: 135-185
特异性
This antibody detects endogenous levels of FACR1 at Human/Mouse/Rat
基因名称
FAR1 MLSTD2 UNQ2423/PRO4981
蛋白名称
FACR1
Organism-1
Human
基因ID-1
84188
SwissProt-1
Q8WVX9
Organism-2
Mouse
基因ID-2
67420
SwissProt-2
Q922J9
Organism-3
Rat
基因ID-3
293173
SwissProt-3
Q66H50
背景
The protein encoded by this gene is required for the reduction of fatty acids to fatty alcohols, a process that is required for the synthesis of monoesters and ether lipids. NADPH is required as a cofactor in this reaction, and 16-18 carbon saturated and unsaturated fatty acids are the preferred substrate. This is a peroxisomal membrane protein, and studies suggest that the N-terminus contains a large catalytic domain located on the outside of the peroxisome, while the C-terminus is exposed to the matrix of the peroxisome. Studies indicate that the regulation of this protein is dependent on plasmalogen levels. Mutations in this gene have been associated with individuals affected by severe intellectual disability, early-onset epilepsy, microcephaly, congenital cataracts, growth retardation, and spasticity (PMID: 25439727). A pseudogene of this gene is located on chromosome 13. [provided by RefSeq, Jan 2015],
细胞定位
Peroxisome membrane ; Single-pass membrane protein .
