FGF-2 Polyclonal Antibody
¥680.00
- 产品信息
商品描述
靶点-Target
MSH5
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
92kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human MSH5 AA range: 13-63
特异性
This antibody detects endogenous levels of MSH5 at Human/Mouse/Rat
基因名称
MSH5
蛋白名称
MSH5
Organism-1
Human
基因ID-1
4439
SwissProt-1
O43196
Organism-2
Mouse
基因ID-2
17687
SwissProt-2
Q9QUM7
Organism-3
Rat
基因ID-3
294252
SwissProt-3
Q6MG62
背景
This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011],
细胞定位
synaptonemal complex,mismatch repair complex,
