- 产品信息
商品描述
靶点-Target
DCK
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
29kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human DCK AA range: 62-112
特异性
This antibody detects endogenous levels of DCK at Human/Mouse/Rat
基因名称
DCK
蛋白名称
DCK
Organism-1
Human
基因ID-1
1633
SwissProt-1
P27707
Organism-2
Mouse
基因ID-2
13178
SwissProt-2
P43346
Organism-3
Rat
基因ID-3
79127
SwissProt-3
P48769
背景
Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity. [provided by RefSeq, Jul 2008],
细胞定位
Nucleus .





