- 产品信息
商品描述
靶点-Target
AP4E1
反应性
Human,Mouse
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
125kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human AP4E1 AA range: 104-154
特异性
This antibody detects endogenous levels of AP4E1 at Human/Mouse
基因名称
AP4E1
蛋白名称
AP4E1
Organism-1
Human
基因ID-1
23431
SwissProt-1
Q9UPM8
Organism-2
Mouse
基因ID-2
108011
SwissProt-2
Q80V94
背景
This gene encodes a member of the adaptor complexes large subunit protein family. These proteins are components of the heterotetrameric adaptor protein complexes, which play important roles in the secretory and endocytic pathways by mediating vesicle formation and sorting of integral membrane proteins. The encoded protein is a large subunit of adaptor protein complex-4, which is associated with both clathrin- and nonclathrin-coated vesicles. Disruption of this gene may be associated with cerebral palsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011],
细胞定位
Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein .





