- 产品信息
商品描述
靶点-Target
TYDP1
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
67kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human TYDP1 AA range: 426-476
特异性
This antibody detects endogenous levels of TYDP1 at Human/Mouse/Rat
基因名称
TDP1
蛋白名称
TYDP1
Organism-1
Human
基因ID-1
55775
SwissProt-1
Q9NUW8
Organism-2
Mouse
SwissProt-2
Q8BJ37
Organism-3
Rat
基因ID-3
314380
SwissProt-3
Q4G056
背景
The protein encoded by this gene is involved in repairing stalled topoisomerase I-DNA complexes by catalyzing the hydrolysis of the phosphodiester bond between the tyrosine residue of topoisomerase I and the 3-prime phosphate of DNA. This protein may also remove glycolate from single-stranded DNA containing 3-prime phosphoglycolate, suggesting a role in repair of free-radical mediated DNA double-strand breaks. This gene is a member of the phospholipase D family and contains two PLD phosphodiesterase domains. Mutations in this gene are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1). [provided by RefSeq, Aug 2016],
细胞定位
Nucleus . Cytoplasm .





