- 产品信息
商品描述
靶点-Target
USH2A
反应性
Human,Mouse,Rat
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
572kD
推荐稀释比
IHC 1:50-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human USH2A AA range: 3731-3781
特异性
This antibody detects endogenous levels of USH2A at Human/Mouse/Rat
基因名称
USH2A
蛋白名称
USH2A
Organism-1
Human
基因ID-1
7399
SwissProt-1
O75445
Organism-2
Mouse
基因ID-2
22283
SwissProt-2
Q2QI47
Organism-3
Rat
基因ID-3
289369
SwissProt-3
Q8K3K1
背景
This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
细胞定位
Cell projection, stereocilium membrane ; Single-pass type I membrane protein . Component of the interstereocilia ankle links in the inner ear sensory cells. In photoreceptors, localizes at a plasma membrane microdomain in the apical inner segment that surrounds the connecting cilia called periciliary membrane complex. .; [Isoform 2]: Secreted.





