USH2A rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2618340

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商品描述
  • 靶点-Target

    USH2A

  • 反应性

    Human,Mouse,Rat

  • 应用

    IHC,IF

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    572kD

  • 推荐稀释比

    IHC 1:50-200;IF 1:50-200

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human USH2A AA range: 3731-3781

  • 特异性

    This antibody detects endogenous levels of USH2A at Human/Mouse/Rat

  • 基因名称

    USH2A

  • 蛋白名称

    USH2A

  • Organism-1

    Human

  • 基因ID-1

    7399

  • SwissProt-1

    O75445

  • Organism-2

    Mouse

  • 基因ID-2

    22283

  • SwissProt-2

    Q2QI47

  • Organism-3

    Rat

  • 基因ID-3

    289369

  • SwissProt-3

    Q8K3K1

  • 背景

    This gene encodes a protein that contains laminin EGF motifs, a pentaxin domain, and many fibronectin type III motifs. The protein is found in the basement membrane, and may be important in development and homeostasis of the inner ear and retina. Mutations within this gene have been associated with Usher syndrome type IIa and retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],

  • 细胞定位

    Cell projection, stereocilium membrane ; Single-pass type I membrane protein . Component of the interstereocilia ankle links in the inner ear sensory cells. In photoreceptors, localizes at a plasma membrane microdomain in the apical inner segment that surrounds the connecting cilia called periciliary membrane complex. .; [Isoform 2]: Secreted.