- 产品信息
商品描述
靶点-Target
SNF8
反应性
Human,Mouse,Rat
应用
WB,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
28kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human SNF8 AA range: 78-128
特异性
This antibody detects endogenous levels of SNF8 at Human/Mouse/Rat
基因名称
SNF8 EAP30
蛋白名称
SNF8
Organism-1
Human
基因ID-1
11267
SwissProt-1
Q96H20
Organism-2
Mouse
基因ID-2
27681
SwissProt-2
Q9CZ28
Organism-3
Rat
基因ID-3
287645
SwissProt-3
Q5RK19
背景
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015],
细胞定位
Cytoplasm. Endosome membrane. Nucleus . Late endosome membrane. Recruited to the endosome membrane to participate in vesicle formation.





