- 产品信息
商品描述
靶点-Target
NAT8L
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
33kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human NAT8L AA range: 218-268
特异性
This antibody detects endogenous levels of NAT8L at Human/Mouse/Rat
基因名称
NAT8L CML3
蛋白名称
NAT8L
Organism-1
Human
基因ID-1
339983
SwissProt-1
Q8N9F0
Organism-2
Mouse
基因ID-2
269642
SwissProt-2
Q3UGX3
Organism-3
Rat
基因ID-3
289727
SwissProt-3
D3ZVU9
背景
This gene encodes a single-pass membrane protein, which contains a conserved sequence of the GCN5 or NAT superfamily of N-acetyltransferases and is a member of the N-acyltransferase (NAT) superfamily. This protein is a neuron-specific protein and is the N-acetylaspartate (NAA) biosynthetic enzyme, catalyzing the NAA synthesis from L-aspartate and acetyl-CoA. NAA is a major storage and transport form of acetyl coenzyme A specific to the nervous system. The gene mutation results in primary NAA deficiency (hypoacetylaspartia). [provided by RefSeq, Dec 2010],
细胞定位
Cytoplasm . Microsome membrane ; Single-pass membrane protein . Mitochondrion membrane ; Single-pass membrane protein . Endoplasmic reticulum membrane ; Single-pass membrane protein . Its enzymatic activity contribution is quantitatively larger in mitochondrial compartment than in extramitochondrial compartment. .





