- 产品信息
商品描述
靶点-Target
OTOG
反应性
Human,Mouse
应用
IHC,IF
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
322kD
推荐稀释比
IHC 1:50-200;IF 1:50-200
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human OTOG AA range: 2706-2756
特异性
This antibody detects endogenous levels of OTOG at Human/Mouse
基因名称
OTOG OTGN
蛋白名称
OTOG
Organism-1
Human
基因ID-1
340990
SwissProt-1
Q6ZRI0
Organism-2
Mouse
SwissProt-2
O55225
背景
The protein encoded by this gene is a component of the acellular membranes of the inner ear. Disruption of the orthologous mouse gene shows that it plays a role in auditory and vestibular functions. It is involved in fibrillar network organization, the anchoring of otoconial membranes and cupulae to the neuroepithelia, and likely in sound stimulation resistance. Mutations in this gene cause autosomal recessive nonsyndromic deafness, type 18B. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2014],
细胞定位
Apical cell membrane ; Peripheral membrane protein ; Extracellular side . Secreted, extracellular space . Found in fiber-like structures during the maturation process of the tectorial membrane. .





