- 产品信息
商品描述
靶点-Target
COMP
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
83kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human COMP AA range: 628-678
特异性
This antibody detects endogenous levels of COMP at Human/Mouse/Rat
基因名称
COMP
蛋白名称
COMP
Organism-1
Human
基因ID-1
1311
SwissProt-1
P49747
Organism-2
Mouse
基因ID-2
12845
SwissProt-2
Q9R0G6
Organism-3
Rat
基因ID-3
25304
SwissProt-3
P35444
背景
The protein encoded by this gene is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Contraction or expansion of a 5 aa aspartate repeat and other mutations can cause pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED). [provided by RefSeq, Jul 2016],
细胞定位
Secreted, extracellular space, extracellular matrix .





