- 产品信息
商品描述
靶点-Target
MYT1L
反应性
Human,Mouse,Rat
应用
WB,ELISA,IHC
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
130kD
推荐稀释比
WB 1:500-2000;IHC 1:50-300;ELISA 1:2000-20000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human MYT1L AA range: 595-645
特异性
This antibody detects endogenous levels of MYT1L at Human/Mouse/Rat
基因名称
MYT1L KIAA1106
蛋白名称
MYT1L
Organism-1
Human
基因ID-1
23040
SwissProt-1
Q9UL68
Organism-2
Mouse
SwissProt-2
P97500
Organism-3
Rat
基因ID-3
116668
SwissProt-3
P70475
背景
This gene encodes a member of the zinc finger superfamily of transcription factors. The encoded protein belongs to a novel class of cystein-cystein-histidine-cystein zinc finger proteins that function in the developing mammalian central nervous system. Forced expression of this gene in combination with the basic helix-loop-helix transcription factor NeuroD1 and the transcription factors POU class 3 homeobox 2 and achaete-scute family basic helix-loop-helix transcription factor 1 can convert fetal and postnatal human fibroblasts into induced neuronal cells, which are able to generate action potentials. Mutations in this gene have been associated with autosomal mental retardation-39 and autism spectrum disorder. Alternative splicing results in multiple variants. [provided by RefSeq, Aug 2016],
细胞定位
Nucleus . Chromosome . Preferentially binds to DNA binding sites that are in an open chromatin configuration. .





