- 产品信息
商品描述
靶点-Target
ADCYA
反应性
Human,Mouse,Rat
应用
WB
宿主物种-Host Species
Rabbit
同种型-Isotype
IgG
修饰-Modification
Unmodified
MW(Calculated)
177kD
推荐稀释比
WB 1:500-2000
组成
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
纯化工艺
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
储存
-15°C to -25°C/1 year(Do not lower than -25°C)
浓度
1 mg/ml
克隆性
Polyclonal
免疫原
Synthesized peptide derived from human ADCYA AA range: 368-418
特异性
This antibody detects endogenous levels of ADCYA at Human/Mouse/Rat
基因名称
ADCY10 SAC
蛋白名称
ADCYA
Organism-1
Human
基因ID-1
55811
SwissProt-1
Q96PN6
Organism-2
Mouse
基因ID-2
271639
SwissProt-2
Q8C0T9
Organism-3
Rat
基因ID-3
59320
SwissProt-3
Q9Z286
背景
The protein encoded by this gene belongs to a distinct class of adenylyl cyclases that is soluble and insensitive to G protein or forskolin regulation. Activity of this protein is regulated by bicarbonate. Variation at this gene has been observed in patients with absorptive hypercalciuria. Alternatively spliced transcript variants encoding different isoforms have been observed. There is a pseudogene of this gene on chromosome 6. [provided by RefSeq, Jul 2014],
细胞定位
Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytoskeleton . Cytoplasm, perinuclear region . Nucleus . Cell projection, cilium . Cytoplasm . Mitochondrion . Distributed to subcellular compartments containing cAMP targets. Found as a plasma membrane-associated protein, protein concentrated in the perinuclear region and protein colocalized with actin or tubulin. .





