RN112 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2618150

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商品描述
  • 靶点-Target

    RN112

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    69kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human RN112 AA range: 377-427

  • 特异性

    This antibody detects endogenous levels of RN112 at Human/Mouse/Rat

  • 基因名称

    RNF112 BFP ZNF179

  • 蛋白名称

    RN112

  • Organism-1

    Human

  • 基因ID-1

    7732

  • SwissProt-1

    Q9ULX5

  • Organism-2

    Mouse

  • 基因ID-2

    22671

  • SwissProt-2

    Q96DY5

  • Organism-3

    Rat

  • 基因ID-3

    24916

  • SwissProt-3

    O70418

  • 背景

    This gene encodes a member of the RING finger protein family of transcription factors. The protein is primarily expressed in brain. The gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008],

  • 细胞定位

    Membrane ; Multi-pass membrane protein . Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus . Nucleus, nuclear body . Nucleus, nucleoplasm . Endosome . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle . Cell junction, synapse, postsynaptic density . Perikaryon . Cell projection, neuron projection . Predominantly in the nucleus, but some amounts were also found in the cytoplasm. Oxidative stress stimulates its shuttling from the cytoplasm into the nucleus. Recruited to nuclear bodies via its interaction with ZBTB16. Localizes to the cell soma and neuritis and only slightly to the nucleus in the neurons of most brain areas. .