RINI rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2618149

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商品描述
  • 靶点-Target

    RINI

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB,IHC

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    51kD

  • 推荐稀释比

    WB 1:500-2000;IHC 1:50-300

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human RINI AA range: 273-323

  • 特异性

    This antibody detects endogenous levels of RINI at Human/Mouse/Rat

  • 基因名称

    RNH1 PRI RNH

  • 蛋白名称

    RINI

  • Organism-1

    Human

  • 基因ID-1

    6050

  • SwissProt-1

    P13489

  • Organism-2

    Mouse

  • 基因ID-2

    107702

  • SwissProt-2

    Q91VI7

  • Organism-3

    Rat

  • 基因ID-3

    100360501

  • SwissProt-3

    P29315

  • 背景

    Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.[supplied by OMIM, Jul 2010],

  • 细胞定位

    Cytoplasm.