CRY2 rabbit pAb

活动价:

¥680.00

市场价:¥880.00

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产品规格:
  • 50μL
  • 100μL
货号:

FAB2618103

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商品描述
  • 靶点-Target

    CRY2

  • 反应性

    Human,Mouse,Rat

  • 应用

    WB

  • 宿主物种-Host Species

    Rabbit

  • 同种型-Isotype

    IgG

  • 修饰-Modification

    Unmodified

  • MW(Calculated)

    65kD

  • 推荐稀释比

    WB 1:500-2000

  • 组成

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • 纯化工艺

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • 储存

    -15°C to -25°C/1 year(Do not lower than -25°C)

  • 浓度

    1 mg/ml

  • 克隆性

    Polyclonal

  • 免疫原

    Synthesized peptide derived from human CRY2 AA range: 181-231

  • 特异性

    This antibody detects endogenous levels of CRY2 at Human/Mouse/Rat

  • 基因名称

    CRY2 KIAA0658

  • 蛋白名称

    CRY2

  • Organism-1

    Human

  • 基因ID-1

    1408

  • SwissProt-1

    Q49AN0

  • Organism-2

    Mouse

  • 基因ID-2

    12953

  • SwissProt-2

    Q9R194

  • Organism-3

    Rat

  • 基因ID-3

    170917

  • SwissProt-3

    Q923I8

  • 背景

    This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2014],

  • 细胞定位

    Cytoplasm . Nucleus . Translocated to the nucleus through interaction with other Clock proteins such as PER2 or ARNTL.